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Related Experiment Videos

Trends in CAPD technique failure: Canada, 1981-1997.

D E Schaubel1, P G Blake, S S Fenton

  • 1Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, USA.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|October 6, 2001
PubMed
Summary

Continuous ambulatory peritoneal dialysis (CAPD) technique failure rates have decreased, particularly due to reduced peritonitis. However, failures from inadequate dialysis have increased, necessitating further data collection for improved patient outcomes.

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Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Dialysis Techniques

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) has seen numerous improvements.
  • Limited research exists on long-term CAPD technique failure rate trends.
  • Quantifying CAPD's benefits requires understanding technique failure evolution.

Purpose of the Study:

  • To analyze trends in CAPD technique failure rates over time in Canada.
  • To assess the impact of improvements on CAPD patient outcomes.
  • To identify specific causes of technique failure and their trends.

Main Methods:

  • Study population: 7110 patients initiating CAPD between 1981 and 1997.
  • Outcome measured: Technique failure, defined as a switch to hemodialysis.

Related Experiment Videos

  • Statistical analysis: Poisson regression adjusted for multiple covariates.

    • Main Results:

    • Overall CAPD technique failure rate was 154.0/1000 patient-years.
    • Failure rates significantly decreased in 1990-93, 1994-95, and 1996-97 compared to 1981-89.
    • Peritonitis-related failures decreased significantly (RR=0.46), but inadequate dialysis failures increased (RR=1.68).

    Conclusions:

    • CAPD technique failure rates have declined, with peritonitis being a major factor.
    • Increased technique failure due to inadequate dialysis requires further investigation.
    • More detailed data on practice patterns are needed to understand cause-effect relationships and guide clinical decisions.