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Related Experiment Videos

Globoid cell leukodystrophy in a Beagle.

G R Johnson, J E Oliver, R Selcer

    Journal of the American Veterinary Medical Association
    |September 11, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Globoid cell leukodystrophy, a rare neurological disorder, was diagnosed in a Beagle. Findings in this dog align with globoid cell leukodystrophy in humans and other animals, suggesting a genetic basis.

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    Area of Science:

    • Veterinary Neurology
    • Canine Genetics
    • Lysosomal Storage Diseases

    Background:

    • Globoid cell leukodystrophy (GLD) is a rare, inherited lysosomal storage disease affecting the white matter of the central nervous system.
    • GLD has been documented in various species, including humans, cats, and several dog breeds, presenting with similar clinical and pathological features.
    • The genetic basis and specific breed predispositions for GLD in dogs are not fully elucidated.