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Updated: Oct 4, 2026

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
Published on: February 9, 2022
Comparison of the forced oscillation technique and the interrupter technique for assessing airway obstruction and its
C Delacourt1, H Lorino, C Fuhrman
1Service de Pédiatrie and Service de Pneumologie, Centre Hospitalier Intercommunal de Créteil, 94000 Créteil, France. christophe.delacourt@chicreteil.fr
Insights
Forced oscillation technique (FOT) is more reliable than the interrupter technique for assessing airway obstruction and reversibility in children with asthma. FOT offers better sensitivity and specificity, especially in younger children.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
- Diagnostic Techniques
Background:
- Assessing airway obstruction in children requires methods with minimal patient cooperation.
- Forced oscillation technique (FOT) and interrupter technique (IT) are suitable for pediatric use due to passive cooperation requirements.
Purpose of the Study:
- To compare the sensitivity and specificity of FOT and IT for detecting airway obstruction and reversibility in children.
- To evaluate the effectiveness of these techniques in asthmatic children aged 3-16 years.
Main Methods:
- 118 children (3-16 yr) with asthma or chronic nocturnal cough participated.
- Forced oscillation technique (R(0), R(16)) and interrupter technique (Rint) parameters were measured.
- Measurements were taken at baseline and post-bronchodilator inhalation.
- Parameters were normalized for height and weight [R(SD)].
Main Results:
- R(0)(SD) showed better discrimination for airway obstruction than Rint(SD) at 80% specificity (66% vs 33% sensitivity).
- DeltaR(0)(SD) demonstrated superior discrimination for bronchodilator reversibility compared to DeltaRint(SD) (67% vs 58% sensitivity at 80% specificity).
- FOT identified a subgroup of young children with reversible high resistance, unlike IT.
Conclusions:
- Forced oscillation technique (FOT) provides a more reliable evaluation of bronchial obstruction and reversibility in asthmatic children over 3 years old.
- FOT is particularly advantageous in young children with high baseline airway resistance.
- FOT offers superior diagnostic accuracy compared to the interrupter technique in this pediatric population.
Abstract:
The forced oscillation technique (FOT) and interrupter technique are particularly attractive for pediatric use as they require only passive cooperation from the patient. We compared the sensitivity and specificity of these methods for detecting airway obstruction and its reversibility in 118 children (3-16 yr) with asthma or chronic nocturnal cough. FOT (R(0) and R(16)) and interruption (Rint) parameters were measured at baseline and after bronchodilator inhalation (n = 94). Rint was significantly lower than R(0), especially in children with high baseline values. Baseline parameters were normalized for height and weight [R(SD)]. In children able to perform forced expiratory maneuvers (n = 93), the best discrimination between those with baseline FEV(1) < 80% or > or = 80% of predicted values was obtained with R(0)(SD). At a specificity of 80%, R(0)(SD) yielded 66% sensitivity, whereas Rint(SD) yielded only 33% sensitivity. Similarly, postbronchodilator changes in R(0)(SD) [DeltaR(0)(SD)] yielded the best discrimination between children with and without significant reversibility in FEV(1). At a specificity of 80%, DeltaR(0)(SD) yielded 67% sensitivity and DeltaRint(SD) yielded 58% sensitivity. In children unable to perform forced expiratory maneuvers (n = 25), FOT, contrary to the interrupter technique, clearly identified a subgroup of young children with high resistance values at baseline, which returned to normal after bronchodilation. We conclude that, in asthmatic children over 3 yr old, FOT measurements provide a more reliable evaluation of bronchial obstruction and its reversibility compared with the interrupter technique, especially in young children with high baseline values.
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