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[Paroxysmal nocturnal hemoglobinuria: pathogenic and therapeutic news]

E Sánchez Pérez1, T García Benayas, M Bretón Arranz

  • 1Servicio de Medicina Interna II, Hospital Clínico Universitario San Carlos, Madrid.

Anales De Medicina Interna (Madrid, Spain : 1984)
|October 9, 2001
PubMed

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All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...