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Related Experiment Videos

Retinal vasculitis associated with chickenpox.

Y H Kuo1, Y Yip, S N Chen

  • 1Department of Ophthalmology, Chang Gung Memorial Hospital, 5 Fu-Shing St., Guei-Shan Hsian, Taoyuan, Taiwan. yahuikuo@tpts5.seed.net.tw

American Journal of Ophthalmology
|October 9, 2001
PubMed
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Retinal vasculitis, a rare complication of chickenpox (varicella), can affect immunocompetent adults. Prompt treatment with acyclovir can resolve this vision-threatening condition.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Retinal Vascular Diseases

Background:

  • Chickenpox (varicella) is a common viral infection, typically self-limiting in immunocompetent individuals.
  • Ocular complications of varicella are uncommon in adults, especially in immunocompetent patients.
  • Retinal vasculitis is an inflammation of retinal blood vessels, potentially leading to vision loss.

Observation:

  • A 32-year-old immunocompetent Asian female presented with blurred vision in the left eye two weeks after contracting chickenpox.
  • Ophthalmic examination revealed signs of anterior chamber and vitreous inflammation, along with perivenous exudation and sheathed retinal vessels in the affected eye.
  • Fluorescein angiography demonstrated late staining of retinal vessels without significant leakage.

Findings:

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  • The patient received a 10-day course of acyclovir treatment.
  • Following treatment, visual acuity in the affected eye returned to normal (20/20).
  • Resolution of retinal vasculitis was confirmed post-treatment.

Implications:

  • This case highlights that retinal vasculitis can be a rare but serious complication of primary varicella infection in immunocompetent adults.
  • Early diagnosis and antiviral treatment are crucial for managing varicella-associated retinal vasculitis and preventing long-term visual impairment.
  • Further research may elucidate the specific mechanisms linking varicella infection to retinal vasculitis in certain individuals.