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Sensitivity-encoded spectroscopic imaging.

U Dydak1, M Weiger, K P Pruessmann

  • 1Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.

Magnetic Resonance in Medicine
|October 9, 2001
PubMed
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Sensitivity encoding (SENSE) significantly reduces spectroscopic imaging (SI) scan times by decreasing phase encoding steps. This method, applied to 2D SI, achieves fourfold faster scans in human brain imaging with preserved resolution and signal-to-noise ratio (SNR).

Area of Science:

  • Magnetic Resonance Imaging
  • Spectroscopic Imaging
  • Medical Physics

Background:

  • Conventional fast spectroscopic imaging (SI) techniques accelerate data acquisition by increasing k-space sampling.
  • Sensitivity encoding (SENSE) presents an alternative approach to accelerate SI by reducing phase encoding steps.

Purpose of the Study:

  • To apply and evaluate the Sensitivity Encoding (SENSE) method for accelerating 2D spectroscopic imaging.
  • To assess the feasibility of SENSE in reducing acquisition time while maintaining spectral and spatial resolution and signal-to-noise ratio (SNR).

Main Methods:

  • SENSE was implemented for 2D spectroscopic imaging using a coil array for data acquisition.
  • The method recovers missing k-space information by utilizing the distinct spatial sensitivities of individual coil elements.

Related Experiment Videos

  • Phantom experiments were conducted to demonstrate the basic properties of SENSE-SI, followed by in vivo human brain imaging.

    • Main Results:

    • A fourfold reduction in scan time was achieved using SENSE for 2D spectroscopic imaging.
    • Spectral and spatial resolution were preserved, and a reasonable signal-to-noise ratio (SNR) was maintained.
    • In vivo metabolic imaging of N-acetylaspartate, creatine, and choline in the human brain demonstrated the feasibility of SENSE-SI.

    Conclusions:

    • SENSE is a highly effective method for reducing acquisition time in 2D spectroscopic imaging.
    • The SENSE technique allows for significantly faster scans without compromising image quality or spectral/spatial resolution.
    • SENSE-SI shows promise for in vivo metabolic imaging applications, offering a substantial acceleration of the imaging process.