Spontaneous urinary chemiluminescence and diet. An intervention study in humans

Spontaneous urinary visible chemiluminiscence has been measured in samples from a diet intervention study in humans. For a month, two groups, each of 21 male volunteers, received either a Mediterranean-type diet or an occidental (high-fat) diet. Urinary chemiluminescence levels (in 10(3) cpm) were 8.5 +/- 3.1 and 6.0 +/- 2.0 for the high-fat and Mediterranean-type diets, respectively. The differences obtained were statistically significant. These results reflect differences in the oxidative stress associate to both diets and support the proposal that spontaneous urinary chemiluminiscence constitutes a complementary index of systemic oxidative stress.