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Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors

J Feixas¹, J M Jiménez, N Godessart

¹Almirall Prodesfarma, Research Center, Cardener 68-74, 08024, Barcelona, Spain.

Bioorganic & Medicinal Chemistry Letters

|October 10, 2001

Abstract:

A new series of potent and selective cyclooxygenase-2 inhibitors have been prepared. Some of these compounds show good oral anti-inflammatory activity in rats.

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