Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis

Dimer asymmetry in signaling of blue light sensor histidine kinases.

Science advances·2026

Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase.

The Journal of biological chemistry·2026

Biocatalytic Potential of a Mycobacterial Aminoacylase for Synthesis of N-Acyl-L-Amino Acids in Aqueous Media.

Chembiochem : a European journal of chemical biology·2026

A novel approach to combat Pseudomonas aeruginosa: repurposing pharmaceuticals for inhibition of phospholipase A.

Microbiology spectrum·2026

Resolution of physics and deep learning-based protein engineering filters: A case study with a lipase for industrial substrate hydrolysis.

PloS one·2025

Computationally guided genome rewiring of Escherichia coli and its application for nanopolyethylene terephthalate (PET) biodegradation and upcycling.

Trends in biotechnology·2025

Nickel-Catalyzed H2-Enabled Asymmetric Olefin Isomerization: Direct Access to P-Stereogenic Phospholenes With Adjacent Stereocenters.

Angewandte Chemie (International ed. in English)·2026

Tuning Reaction Pathways by Controlling Atomic Assembly on Oxide Clusters.

Angewandte Chemie (International ed. in English)·2026

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications.

Angewandte Chemie (International ed. in English)·2026

Heterobimetallic Janus Catalysts for the One-Pot Synthesis of Polar-Apolar Block Copolymers.

Angewandte Chemie (International ed. in English)·2026

Closed-Loop Recyclable Solid Polymer Electrolytes via Dynamic Lipoate Cross-Linking.

Angewandte Chemie (International ed. in English)·2026

Asymmetric Kinetic Resolution of 2-Aryl Oxetanes by Dinuclear Titanium Radical Catalysis.

Angewandte Chemie (International ed. in English)·2026

Development of an electrochemical enzymatic lactate sensor covered by a non-volatile poly(vinyl alcohol)-based water-in-eutectogel.

Bioelectrochemistry (Amsterdam, Netherlands)·2026

Selective Enzymatic Synthesis of Glucose Fatty Acid Esters in a Choline Chloride-Glucose Reactive Deep Eutectic Solvent.

ChemSusChem·2026

Biotransformation-guided production of quinalizarin as an antibacterial agent against Acinetobacter baumannii.

Applied microbiology and biotechnology·2026

Selective fractionation and enhanced cellulose accessibility of corn Stover using a cetyltrimethylammonium bromide/ethylene glycol/tartaric acid ternary deep eutectic solvent.

International journal of biological macromolecules·2026

Metabolic engineering of Dunaliella salina enhances astaxanthin production: combined effects of heterologous enzyme co-expression and dual-stress optimization.

World journal of microbiology & biotechnology·2026

Automated high-throughput screening combined with model-assisted analysis enables quantitative identification of process drivers and trade-offs during extracellular Fab production in Escherichia coli.

Bioprocess and biosystems engineering·2026

Related Experiment Videos

Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis

Related Concept Videos

Dimer asymmetry in signaling of blue light sensor histidine kinases.

Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase.

Biocatalytic Potential of a Mycobacterial Aminoacylase for Synthesis of N-Acyl-L-Amino Acids in Aqueous Media.

A novel approach to combat Pseudomonas aeruginosa: repurposing pharmaceuticals for inhibition of phospholipase A.

Resolution of physics and deep learning-based protein engineering filters: A case study with a lipase for industrial substrate hydrolysis.

Computationally guided genome rewiring of Escherichia coli and its application for nanopolyethylene terephthalate (PET) biodegradation and upcycling.

Nickel-Catalyzed H2-Enabled Asymmetric Olefin Isomerization: Direct Access to P-Stereogenic Phospholenes With Adjacent Stereocenters.

Tuning Reaction Pathways by Controlling Atomic Assembly on Oxide Clusters.

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications.

Heterobimetallic Janus Catalysts for the One-Pot Synthesis of Polar-Apolar Block Copolymers.

Closed-Loop Recyclable Solid Polymer Electrolytes via Dynamic Lipoate Cross-Linking.

Asymmetric Kinetic Resolution of 2-Aryl Oxetanes by Dinuclear Titanium Radical Catalysis.

Development of an electrochemical enzymatic lactate sensor covered by a non-volatile poly(vinyl alcohol)-based water-in-eutectogel.

Selective Enzymatic Synthesis of Glucose Fatty Acid Esters in a Choline Chloride-Glucose Reactive Deep Eutectic Solvent.

Biotransformation-guided production of quinalizarin as an antibacterial agent against Acinetobacter baumannii.

Selective fractionation and enhanced cellulose accessibility of corn Stover using a cetyltrimethylammonium bromide/ethylene glycol/tartaric acid ternary deep eutectic solvent.

Metabolic engineering of Dunaliella salina enhances astaxanthin production: combined effects of heterologous enzyme co-expression and dual-stress optimization.

Automated high-throughput screening combined with model-assisted analysis enables quantitative identification of process drivers and trade-offs during extracellular Fab production in Escherichia coli.

Related Experiment Videos

Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis

Related Concept Videos

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