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SW-163C and E, novel antitumor depsipeptides produced by Streptomyces sp. II. Structure elucidation
K Takahashi1, H Koshino, Y Esumi
1Research Institute of Life Science, Snow Brand Milk Products Co., Ltd., Tochigi, Japan. k-takahashi@snowbrand.co.jp
The Journal of Antibiotics
|October 11, 2001
Abstract:
SW-163C and E are novel antitumor antibiotics, which belong to quinomycin family, isolated from the culture broth of Streptomyces sp. SNA15896. These compounds were determined to be cyclic depsipeptides having 3-hydroxyquinaldic acid as a chromophore and a sulfur-containing intramolecular cross linkage through various spectroscopic analyses.