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Screening for celiac disease in children with recurrent abdominal pain

K P Fitzpatrick1, P M Sherman, M Ipp

  • 1Division of Gastroenterology and Nutrition, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

Journal of Pediatric Gastroenterology and Nutrition
|October 11, 2001
PubMed

Insights

This study found no increased prevalence of antiendomysial antibodies in children with recurrent abdominal pain compared to healthy children. These findings do not support routine celiac disease screening for children with this symptom in primary care.

Area of Science:

  • Pediatric Gastroenterology
  • Immunology
  • Clinical Diagnostics

Background:

  • Celiac disease is a gluten intolerance often presenting with chronic abdominal pain.
  • Recurrent abdominal pain is a common complaint in pediatric primary care.

Purpose of the Study:

  • To investigate the prevalence of antiendomysial antibodies in children experiencing recurrent abdominal pain.
  • To compare this prevalence with that in healthy children.

Main Methods:

  • A community-based case-control study involving children with recurrent abdominal pain and healthy controls.
  • Measurement of antiendomysial antibodies in serum samples from both groups.

Main Results:

  • Out of 173 participants, only 2 (1.2%) tested positive for antiendomysial antibodies.
  • The prevalence was 1% in children with recurrent abdominal pain and 1% in controls, with no statistically significant difference.

Conclusions:

  • No association was found between recurrent abdominal pain and antiendomysial antibody prevalence in this study.
  • Screening for celiac disease in children with recurrent abdominal pain in primary care is not supported by these data.
Abstract

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