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Molecular characterization of DDX26, a human DEAD-box RNA helicase, located on chromosome 7p12

A A Camargo1, D N Nunes, H B Samaia

  • 1Instituto Ludwig de Pesquisa sobre o Câncer, São Paulo, SP, Brasil. anamaria@compbio.ludwig.org.br

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
|October 11, 2001
PubMed

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Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...