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Interstitial brachytherapy using iridium-192 for malignant brain tumors: clinical results
1Neurosurgical Center of PLA, Department of Neurosurgery, Navy General Hospital, Beijing.
Objective:
To determine the effects and toxicity of interstitial brachytherapy using iridium-192 on brain malignant gliomas.
Methods:
Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high-activity iridium-192 sources.
Results:
The median survival for patients receiving brachytherapy was 28 months. The survival rates at 1, 2, 3 years were 92.8%, 83.9% and 71.4% respectively.
Conclusions:
Brachytherapy may improve the control of local tumor and prolong the survival, when used in deep malignant brain gliomas, by temporary implanted high doses of iridium-192 sources.