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Updated: Aug 12, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[Radiochemotherapy of urothelial carcinoma]
H Büttner1, T Feyerabend, A Böhle
1Klinik und Poliklinik für Urologie, Universitätsklinikum Lübeck, Ratzeburger Allee 160, 23538 Lübeck. hartwig.buettner@medinf.mu-luebeck.de
Abstract:
Radical cystectomy is the current standard therapy for muscle invasive or locally advanced transitional cell carcinoma of the bladder. Organ-preserving monotherapeutic alternatives (e.g. transurethral resection, radiotherapy) do not lead to similar cure rates. In selected cases, a trimodal approach using transurethral resection and combined radio- and chemotherapy can be as efficient as cystectomy.
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