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A short and efficient route to novel scyphostatin analogues
1Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.
Organic Letters
|October 12, 2001
Abstract:
[structure: see text]. Several novel scyphostatin analogues have been prepared in up to 18% yield over five steps from commercially available 4-bromoguaiacol, utilizing an organometallic addition to afford the desired syn-hydroxy-epoxides.