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A hypothesis about tumour development and the clinical features of hereditary breast cancers
1Department of Oncology and Department of Cancer Epidemiology, University Hospital, S-22185, Lund, Sweden. hakan.olsson@onk.lu.se
European Journal of Cancer (Oxford, England : 1990)
|October 13, 2001
Abstract:
A unifying hypothesis is presented about tumour biology in hereditary breast cancer in relation to the epithelial origin and the degree of differentiation of the normal epithelium at the time of tumour initiation. By using different breast cancer syndromes as examples, it is possible to, at least partly, predict the tumour biology, clinical presentation and therapeutic response.