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Updated: Aug 2, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
Published on: June 11, 2015
Studies on 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase using chorismate mutase inhibitors
M R Birck1, A Husain, G Y Sheflyan
1Department of Medicinal Chemistry, 428 Church St., University of Michigan, Ann Arbor, 48109-1065, USA.
Abstract:
The proposed cyclic mechanism of 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase and the mechanism of chorismate mutase share certain structural and electronic similarities. In this report, we examine several inhibitors of chorismate mutase for their efficacy against KDO 8-P synthase.
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