Gene regulation and targeting in the kidney: relevance to renal physiology and pathophysiology
Related Experiment Video
Updated: Oct 4, 2026
10:31
Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
G Capasso1, M Rizzo, F Morelli
1Chair of Nephrology, School of Medicine, Faculty of Medicine, Second University of Naples, Naples, Italy. gb.capasso@unina2.it
Nephron
|October 13, 2001
Abstract
No abstract available in PubMed .
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The urinary system consists of two kidneys, two ureters, the urinary bladder, and the urethra.
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The kidneys are bean-shaped organs located in the retroperitoneal space, on either side of the vertebral column, between the T12 and L3 vertebrae. They are partially protected by the rib cage and surrounded by perirenal fat, which provides cushioning. They are responsible for urine formation and play critical roles in regulating blood pressure, electrolyte levels, and hormone production. The ureters...
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The Glomerular Filtration Rate (GFR) is a measure of kidney function, reflecting the volume of filtrate formed per minute in the kidneys. On average, GFR is approximately 125 mL/min in males and 105 mL/min in females. Maintaining a relatively constant GFR is essential for the kidneys to effectively regulate body fluid homeostasis and maintain extracellular stability.
GFR regulation involves two primary intrinsic controls: the myogenic and tubuloglomerular feedback mechanisms.
The myogenic...
GFR regulation involves two primary intrinsic controls: the myogenic and tubuloglomerular feedback mechanisms.
The myogenic...
01:33Hormonal Regulation
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01:10Nephrons
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