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MCPA permeation through protective gloves.

J T Purdham1, B J Menard, P R Bozek

  • 1Department of Public Health Sciences, University of Toronto, Ontario, Canada.

Applied Occupational and Environmental Hygiene
|October 16, 2001
PubMed
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This study evaluated herbicide permeation through gloves. Nitrile gloves offered the best protection against the ester form of 4-chloro-2-methylphenoxyacetic acid (MCPA), while all gloves protected against the salt form.

Area of Science:

  • Agricultural Chemistry
  • Occupational Safety and Health
  • Materials Science

Background:

  • 4-chloro-2-methylphenoxyacetic acid (MCPA) is a widely used herbicide.
  • Understanding herbicide permeation through protective gloves is crucial for agricultural worker safety.
  • Commercial MCPA formulations exist as salt and ester forms, potentially exhibiting different permeation characteristics.

Purpose of the Study:

  • To assess the permeation of MCPA salt and ester formulations through common protective glove materials.
  • To provide data for selecting appropriate personal protective equipment (PPE) for handling MCPA herbicides.
  • To compare the protective efficacy of natural rubber, neoprene, nitrile, and Viton-coated chloroprene gloves.

Main Methods:

  • Permeation testing was conducted using the ASTM F739-91 standard method.

Related Experiment Videos

  • Two undiluted MCPA formulations (salt and ester) were tested against four glove types.
  • High-Performance Liquid Chromatography with Ultraviolet detection (HPLC-UV) was used to quantify MCPA permeation.

    • Main Results:

    • No significant permeation of the MCPA salt formulation was observed across any glove type within 24 hours.
    • The MCPA ester formulation showed varying permeation rates, with nitrile gloves exhibiting the lowest (0.04 microg x cm(-2) min(-1)) and neoprene the highest (0.21 microg x cm(-2) min(-1)).
    • All tested glove materials experienced significant swelling (approx. 30% increase in thickness) when exposed to the ester formulation.

    Conclusions:

    • All four glove types provide adequate protection against the MCPA salt formulation.
    • All glove types offer at least eight hours of protection against the MCPA ester formulation.
    • The salt formulation of MCPA herbicide is recommended over the ester formulation due to lower permeation risk.