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Related Experiment Videos

Swallowing problems in post irradiated NPC patients.

P Mok1, R S Seshadri, J K Siow

  • 1Department of Otolaryngology, Tan Tock Seng Hospital, Singapore. paul_mok@notes.ttsh.gov.sg

Singapore Medical Journal
|October 16, 2001
PubMed
Summary

Swallowing difficulties, including cranial nerve X and XII palsies, can occur in advanced Nasopharyngeal Carcinoma (NPC) patients post-radiotherapy. Treatment options for these severe swallowing issues are varied and may include surgery or gastrostomy.

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Harmonizing body surface area assessments between the Eczema Area and Severity Index, SCORing Atopic Dermatitis, and handprint methods utilizing one shared measurement-A proposal to improve efficiency and reduce error in atopic dermatitis trials.

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Area of Science:

  • Otolaryngology
  • Oncology
  • Neurology

Background:

  • Nasopharyngeal Carcinoma (NPC) is a malignancy with potential post-treatment complications.
  • Radiotherapy is a primary treatment for advanced NPC, often leading to side effects.

Observation:

  • Three patients with advanced NPC developed significant swallowing problems after radiotherapy.
  • These issues manifested as oral and pharyngeal dysphagia, linked to cranial nerve X and XII palsies.

Findings:

  • No evidence of tumor recurrence or metastasis was found in the patients.
  • Surgical interventions like cricopharyngeal myotomy, medialisation thyroplasty, and percutaneous endoscopic gastrostomy (PEG) were employed with varying outcomes.

Implications:

Related Experiment Videos

  • This case series highlights the potential for severe swallowing dysfunction post-NPC radiotherapy.
  • It underscores the need for effective management strategies for dysphagia in these patients.