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[A surveillance study on penicillin-resistant Streptococcus pneumoniae in China]
1Institute of Clinical Pharmacology, First Hospital of Beijing Medical University, Beijing 100034.
Zhonghua Yi Xue Za Zhi
|October 17, 2001
Summary
Penicillin-resistant Streptococcus pneumoniae strains were identified in China, with a 4% resistance rate. This highlights significant cross-resistance issues in the country.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Research
Context:
- Pediatric respiratory tract infections are common.
- Streptococcus pneumoniae is a significant pathogen.
- Antibiotic resistance is a growing global concern.
Purpose:
- To determine the prevalence of penicillin-resistant Streptococcus pneumoniae (PRSP).
- To assess the antibiotic resistance rates of S. pneumoniae isolates in China.
Summary:
- A study of 989 pediatric patients in China identified Streptococcus pneumoniae isolates.
- Antibiotic susceptibility testing revealed a 4% penicillin resistance rate.
- High resistance rates were observed for erythromycin (54%), clarithromycin (52%), and tetracycline (100%).
Impact:
- The findings confirm the presence of PRSP in China.
- Significant cross-resistance among various antibiotics was noted.
- This underscores the need for ongoing surveillance and antimicrobial stewardship.