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Updated: Oct 4, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Lack of human papillomavirus types 16 and 18 DNA in esophageal squamous carcinoma cell lines
1Department of Cell Biology, Cancer Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. zhengjie@jlonline.com
Objective:
To assess the role of human papillomavirus (HPV) in the carcinogenesis of the esophageal carcinomas in a high-incidence geographical area in Northern China.
Methods:
The presence of HPV types 16 and 18 DNA in the three esophageal carcinoma cell lines was examined by type-specific polymerase chain reaction (PCR).
Results:
No HPV type 16 and 18 DNA was found in any of the three esophageal carcinoma cell lines.
Conclusion:
The results suggest that the role of HPV in human esophageal carcinogenesis in a high-incidence geographical area remains to be elucidated.

