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Synthesis and antimycobacterial activity of 5-aryl-1-isonicotinoyl-3-(pyridin-2-yl)-4, 5-dihydro-1H-pyrazole
M G Mamolo1, D Zampieri, V Falagiani
1Dipartimnento di Scienze Farmaceutiche, Università di Trieste, Italy. mamolo@univ.trieste.it
Farmaco (Societa Chimica Italiana : 1989)
|October 17, 2001
Abstract:
5-Aryl-1-isonicotinoyl-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazole derivatives were synthesized and tested for their in vitro antimycobacterial activity. The compounds showed an interesting activity against a strain of Mycobacterium tuberculosis and a human strain of M. tuberculosis H4.