Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatocellular carcinoma: multimodality management.

K K Christians1, H A Pitt, W S Rilling

  • 1Department of Surgery, Medical College of Wisconsin, Milwaukee, 53226, USA.

Surgery
|October 17, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conscientious objection to medical aid in dying: Knowledge, attitudes, and practices in primary care.

Revista clinica espanola·2025
Same author

Impact of the COVID-19 Pandemic on a Cancer Fast-Track Programme.

Cancer control : journal of the Moffitt Cancer Center·2022
Same author

Angiotensin-converting enzyme inhibitors in preclinical myxomatous mitral valve disease in dogs: systematic review and meta-analysis.

The Journal of small animal practice·2021
Same author

Ten-year assessment of a cancer fast-track programme to connect primary care with oncology: reducing time from initial symptoms to diagnosis and treatment initiation.

ESMO open·2021
Same author

Determinants associated with uncontrolled asthma in Portugal: A national population-based study.

Pulmonology·2020
Same author

Multi-annual survey of health status disturbance in the Bilbao estuary (Bay of Biscay) based on sediment chemistry and juvenile sole (Solea spp.) histopathology.

Marine pollution bulletin·2019
Same journal

Fistulotomy with primary sphincteroplasty for complex anal fistulas: Should we be concerned about incontinence?

Surgery·2026
Same journal

No need for mesh in the repair of hiatal hernias: Autologous tissue hiatoplasty techniques for the repair of the complex diaphragmatic defect.

Surgery·2026
Same journal

Incretin-based therapies and altered myocardial metabolism in a swine model of ischemic heart disease in the setting of metabolic syndrome.

Surgery·2026
Same journal

Colonoscopy utilization and persistent disparities in early onset colorectal cancer: A multistate, multi-institution nested case-control study.

Surgery·2026
Same journal

Preoperative risk assessment for surgical operations using artificial intelligence: Potential benefits, hurdles, and future directions.

Surgery·2026
Same journal

Perioperative outcomes of neoadjuvant immunochemoradiotherapy versus immunochemotherapy followed by surgery in elderly patients with locally advanced esophageal squamous cell carcinoma.

Surgery·2026
See all related articles

Hepatocellular carcinoma treatment options like ablation and surgery offer improved survival. Treatment choice and patient liver function (Child-Pugh classification) are key to outcomes for this common cancer.

Area of Science:

  • Hepatology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Hepatocellular carcinoma (HCC) is a prevalent global malignancy.
  • Surgical resection, the traditional standard, is feasible for a limited patient subset.
  • Emerging treatments include ablative procedures and liver transplantation for HCC management.

Purpose of the Study:

  • To evaluate treatment outcomes for hepatocellular carcinoma (HCC).
  • To compare the efficacy of ablation, resection, and transplantation.
  • To identify factors influencing patient survival in HCC.

Main Methods:

  • A retrospective analysis of 110 HCC patients over six years.
  • Patients received palliative care, chemotherapy, ablation (percutaneous ethanol injection, cryoablation, radiofrequency ablation, chemoembolization), resection, or transplantation.

Related Experiment Videos

  • Treatment modalities were compared based on survival and mortality rates.

    • Main Results:

    • Thirty-day mortality was 3% for ablation and 0% for resection.
    • Median survival: 6 months (no treatment), 27 months (ablation), 35 months (resection), and 53 months (transplantation).
    • Multivariate analysis identified treatment modality and Child-Pugh classification as significant predictors of outcome.

    Conclusions:

    • Hepatocellular carcinoma treatment necessitates a multidisciplinary approach.
    • Ablation and surgical operations are safe and effective treatment options.
    • Optimal HCC management involves selecting treatment modality and considering Child-Pugh classification for patients in classes A and B.