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Updated: Aug 10, 2026

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Published on: November 28, 2010
Heterotopic bone in the ovary associated with a mucinous cystadenoma
1Departments of Obstetrics/Gynecology and Pathology, Wilford Hall U.S. Air Force Medical Center, 2200 Bergquist Drive, Suite 1, Lackland AFB, TX 78236-5300, USA.
Abstract:
Bone formation in the ovary, with the exception of developing in the setting of a mature cystic teratoma, is exceedingly uncommon. We report a case of bone formation within a mucinous cystadenoma of the ovary. A 19-year-old active duty female presented with an asymptomatic pelvic mass; sonographic imaging revealed a 5.7-cm complex right adnexal mass. A laparoscopic cystectomy was performed. Pathologic evaluation of the cyst revealed a mucinous cystadenoma. Contained within several of the thick fibrous septae were areas of well-formed bone. Although a benign finding, bone formation and associated fibrosis may lead to sonographic findings of concern during the evaluation of patients with a pelvic mass.
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