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Desmoplastic melanoma.

W G Payne1, R Kearney, K Wells

  • 1Department of Surgery, University of South Florida, Tampa, USA.

The American Surgeon
|October 18, 2001
PubMed
Summary
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Desmoplastic melanoma, a rare malignant melanoma subtype, often recurs locally. Aggressive local excision and diligent follow-up are crucial for managing this condition and improving patient survival rates.

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Pathology

Background:

  • Desmoplastic melanoma is an uncommon variant of malignant melanoma.
  • It can present as a desmoplastic, neurotropic, or neural transforming subtype.
  • Often appears as an amelanotic nodule or with existing melanocytic lesions.

Purpose of the Study:

  • To evaluate treatment outcomes for desmoplastic melanoma.
  • To assess recurrence rates and survival following local excision.

Main Methods:

  • Retrospective review of 30 patients treated for desmoplastic melanoma over 6 years.
  • All patients underwent local excision.
  • Follow-up averaged 18 months.

Main Results:

Related Experiment Videos

  • Local recurrence occurred in 23% of patients, managed with re-excision.
  • Clinical regional metastasis was detected in 6%.
  • Distant metastasis (lung) occurred in 6%, with 96% overall survival.

Conclusions:

  • Desmoplastic melanoma requires aggressive local excision.
  • Close follow-up is essential for detecting and managing resectable recurrent lesions.
  • Accurate diagnosis can be challenging due to varied presentations.