Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clear cell pleomorphic xanthoastrocytoma: case report.

J Primavera1, D C Nikas, A A Zamani

  • 1Department of Pathology and Neurosurgical Service, Massachusetts General Hospital, Boston, USA.

Acta Neuropathologica
|October 18, 2001
PubMed
Summary

Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic tumor. This case highlights a unique variant with clear cell and papillary features, potentially linked to increased recurrence risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know.

AJNR. American journal of neuroradiology·2022
Same author

Temperature-Dependent Development Modeling of the Phorid Fly Megaselia halterata (Wood) (Diptera: Phoridae).

Neotropical entomology·2016
Same author

Validation of multisociety combined task force definitions of abnormal disk morphology.

AJNR. American journal of neuroradiology·2015
Same author

Life parameters of Tetranychus urticae (Acari: Tetranychidae) on six common bean cultivars.

Journal of economic entomology·2014
Same author

Gain of chromosome arm 1q in atypical meningioma correlates with shorter progression-free survival.

Neuropathology and applied neurobiology·2011
Same author

Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation.

Transplant infectious disease : an official journal of the Transplantation Society·2011

Area of Science:

  • Neuro-oncology
  • Pathology
  • Neurosurgery

Background:

  • Pleomorphic xanthoastrocytoma (PXA) is an astrocytic tumor with generally favorable prognosis after surgical resection.
  • However, some PXA cases exhibit malignant progression and recurrence, necessitating further understanding of prognostic factors.

Observation:

  • A 47-year-old woman presented with a left temporal lobe PXA.
  • The tumor displayed classic PXA features alongside extensive clear cell changes, focal papillary areas, and anaplastic findings.
  • The patient experienced two recurrences following complete surgical resection.

Findings:

  • This case represents a rare histological variant of PXA characterized by prominent clear cell and focal papillary morphology.
  • The observed anaplastic features and multiple recurrences suggest this variant may have a more aggressive clinical course.

Related Experiment Videos

Implications:

  • Further investigation of histologically similar PXA cases is crucial to ascertain if this variant is associated with a higher likelihood of recurrence.
  • Identifying distinct PXA variants can improve prognostic accuracy and guide treatment strategies for patients with this rare brain tumor.