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Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
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Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Published on: August 31, 2016

Trends in transplantation of hematopoietic stem cells from unrelated donors

C Anasetti1, E W Petersdorf, P J Martin

  • 1Department of Medicine, Division of Oncology, University of Washington, Seattle, Washington, USA. canasett@fhcrc.org

Current Opinion in Hematology
|October 18, 2001
PubMed

Transplants of hematopoietic stem cells from unrelated donors have become feasible for patients with a growing variety of hematologic disorders. The probability of finding a suitable donor has increased because of the expansion of the network of registries containing more than seven million HLA-typed donors worldwide. The selection of compatible donors has become more effective, thanks to the discovery of new HLA alleles and the development of precise and efficient HLA typing methods using DNA technology. Improved methods for transplantation may provide the opportunity to further decrease treatment-related toxicity and improve survival.

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