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[A clinical study on patients detected Pasteurella multocida from sputum]
Abstract:
We reported ten cases, (four female and six male), whose sputum cultures positive for Pasteurella multocida from 1990 to 2000. In the past eleven years increasing numbers of cases have appeared in our hospital. The majority of the cases with P. multocida possessed some underlying pulmonary diseases (seven cases, 70%), inactive lung tuberculosis or bronchiectasis. There were compromised hosts such as high ages person, steroids dependent person and diabetes mellitus patients. P. multocida was almost susceptible to antibioticus (penicillin and cephalosporins), although some erythromycin resistant strains were identified. The cats' oral cavities in our two cases were cultured and P. multocida were isolated. In our survey the prevalence of this organism is as high as 85% in cats. Our data suggests that patients who are in the high infection risk category are easily infected to P. multocida.
Insights
Pasteurella multocida infections are increasing, often affecting patients with underlying lung disease or compromised immunity. Cats are a significant reservoir for this bacterium, posing an infection risk.
Area of Science:
- Medical Microbiology
- Infectious Diseases
Context:
- Pasteurella multocida is an opportunistic pathogen.
- An increasing incidence of P. multocida infections has been observed.
- Patients with underlying pulmonary conditions are frequently affected.
Purpose:
- To report on cases of P. multocida infection.
- To identify risk factors and potential sources of infection.
- To assess antibiotic susceptibility.
Summary:
- Ten cases of P. multocida sputum-positive infections were identified between 1990-2000, with a notable increase in the subsequent eleven years.
- The majority of patients (70%) had pre-existing pulmonary diseases like inactive tuberculosis or bronchiectasis.
- Compromised hosts included elderly individuals, steroid-dependent patients, and those with diabetes mellitus.
- P. multocida isolates were generally susceptible to penicillin and cephalosporins, though some erythromycin resistance was noted.
- Oral cavities of cats in two cases yielded P. multocida, with an 85% prevalence in the surveyed cat population, indicating cats as a reservoir.
Impact:
- Highlights the growing threat of P. multocida in clinical settings.
- Identifies high-risk patient populations for targeted prevention.
- Underscores the role of domestic animals, particularly cats, in pathogen transmission.
- Provides insights into antibiotic resistance patterns for treatment guidance.
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