Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cavitations in biological tissues].

J Jenne1

  • 1Radiologische Diagnostik und Therapie Deutsches Krebsforschungszentrum Heidelberg. j.jenne@dkfz.de

Ultraschall in Der Medizin (Stuttgart, Germany : 1980)
|October 19, 2001
PubMed
Summary

While diagnostic ultrasound is popular for its safety, increased machine output can lead to thermal and mechanical effects. The mechanical index helps estimate risks like cavitation, especially with contrast agents, though no adverse effects are reported in humans.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Ultrasound motion tracking for radiation therapy].

Der Radiologe·2015
Same author

The 2014 liver ultrasound tracking benchmark.

Physics in medicine and biology·2015
Same author

Ion beam tracking using ultrasound motion detection.

Medical physics·2014
Same author

Ultrasound tracking for intra-fractional motion compensation in radiation therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2014
Same author

Neurons but not glial cells overexpress ubiquitin in the rat brain following focused ultrasound-induced opening of the blood-brain barrier.

Neuroscience·2010
Same author

Outpatient management of low-velocity gunshot-induced fractures.

Orthopedics·2001

Area of Science:

  • Medical Imaging
  • Biophysics
  • Acoustic Sciences

Background:

  • Diagnostic ultrasound is widely used due to its perceived safety.
  • Increased ultrasound output can elevate risks of thermal and mechanical bioeffects.
  • Understanding these bioeffects is crucial for safe clinical application.

Purpose of the Study:

  • To review the potential thermal and mechanical side effects of diagnostic ultrasound.
  • To discuss the role of the mechanical index in assessing cavitation risk.
  • To examine the impact of contrast agents on ultrasound bioeffects.

Main Methods:

  • Review of existing literature on diagnostic ultrasound bioeffects.
  • Discussion of cavitation mechanisms and their biological consequences.
  • Analysis of the mechanical index and its clinical relevance.
  • Evaluation of studies on ultrasound-induced side effects, particularly with contrast agents.

Main Results:

  • Higher ultrasound output, especially negative peak pressures, increases cavitation risk.
  • Cavitation involves bubble collapse, releasing energy and causing secondary effects.
  • The mechanical index quantifies cavitation likelihood; it's displayed in real-time on machines.
  • Contrast agents enhance cavitation risk; adverse effects observed in animal studies mainly at tissue-gas interfaces or with high contrast concentrations.

Conclusions:

  • No adverse effects of diagnostic ultrasound have been reported in humans.
  • Potential for harm from advanced ultrasound techniques exists.
  • Recommendations for safe diagnostic ultrasound use have been established by organizations like WFUMB.

Related Experiment Videos