Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid hormones and thyrotropin in amniotic fluid.

I J Chopra, B F Crandall

    The New England Journal of Medicine
    |October 9, 1975
    PubMed
    Summary

    Amniotic fluid thyroid hormone levels, particularly 3,3

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Education and testing strategy for large-scale cystic fibrosis carrier screening.

    Journal of genetic counseling·2013
    Same author

    Use of oral cholecystography agents in the treatment of hyperthyroidism of subacute thyroiditis.

    Panminerva medica·2003
    Same author

    Use of oral cholecystographic agents in the treatment of amiodarone-induced hyperthyroidism.

    The Journal of clinical endocrinology and metabolism·2001
    Same author

    A radioimmunoassay for type I iodothyronine 5'-monodeiodinase in human tissues.

    Thyroid : official journal of the American Thyroid Association·2001
    Same author

    Evidence for a role of the type III-iodothyronine deiodinase in the regulation of 3,5,3'-triiodothyronine content in the human central nervous system.

    European journal of endocrinology·2001
    Same author

    A study of iodothyronine 5'-monodeiodinase activities in normal and pathological tissues in man and their comparison with activities in rat tissues.

    Life sciences·2001

    Area of Science:

    • Endocrinology
    • Reproductive Biology
    • Perinatal Medicine

    Background:

    • Thyroid hormones are crucial for fetal development.
    • Accurate assessment of fetal thyroid status is essential.
    • Amniotic fluid may provide insights into fetal thyroid function.

    Purpose of the Study:

    • To measure thyroid hormone and thyrotropin concentrations in amniotic fluid during pregnancy.
    • To compare amniotic fluid thyroid hormone levels with maternal serum levels.
    • To evaluate the diagnostic utility of amniotic fluid thyroid hormones.

    Main Methods:

    • Radioimmunoassays were used to quantify thyroid hormones and thyrotropin.
    • Samples were collected from pregnant women at different gestational ages.
    • Thyroxine, 3,3',5-tri-iodothyronine, and 3,3',5'-tri-iodothyronine were measured.

    Main Results:

    • Thyroxine levels increased with gestational age.
    • 3,3',5-tri-iodothyronine was undetectable, while 3,3',5'-tri-iodothyronine levels were high early in pregnancy, decreasing later.
    • Amniotic fluid hormone profiles differed significantly from maternal serum.

    Conclusions:

    • Amniotic fluid 3,3',5'-tri-iodothyronine levels may help diagnose fetal thyroid dysfunction.
    • Measuring amniotic fluid thyroid hormones can aid in identifying early-stage pregnancies (under 30 weeks).
    • This analysis offers a non-invasive method for assessing fetal thyroid status.

    Related Experiment Videos