The effect of alcohol and barbiturate on the frequency of atrial and ventricular premature beats during sleep

Related Experiment Video

Updated: Aug 18, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
08:45

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

R Feinstein, B A Gooden, S Wolf

    The Pavlovian Journal of Biological Science
    |April 1, 1975
    PubMed

    More Related Videos

    Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice10:56

    Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

    Published on: August 2, 2017

    Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings06:39

    Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

    Published on: June 13, 2025

    Related Concept Videos

    CNS Depressants: Alcohol and Nicotine01:27

    CNS Depressants: Alcohol and Nicotine

    Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
    CNS Depressants: Barbiturates and Benzodiazepines01:14

    CNS Depressants: Barbiturates and Benzodiazepines

    CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
    Sedatives and Hypnotics Drugs: Barbiturates01:20

    Sedatives and Hypnotics Drugs: Barbiturates

    Sedatives and hypnotics encompass a drug class that acts on the central nervous system (CNS) to alleviate anxiety, promote relaxation and induce sleep.These drugs function by amplifying the actions of the neurotransmitter γ-aminobutyric acid (GABA), resulting in reduced neuronal activity. Barbiturates, a subset of sedatives and hypnotics first synthesized in the late 1800s, are categorized into ultra-short, short, intermediate, and long-acting groups based on their duration of effect. A key...
    Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

    Sedatives and Hypnotics Drugs: Miscellaneous Agents

    Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
    Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
    Disturbances in Heart Rhythm01:29

    Disturbances in Heart Rhythm

    Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
    Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
    Substance Use Disorders Affecting Sleep01:24

    Substance Use Disorders Affecting Sleep

    Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
    Understanding the concepts of physical dependence,...