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Related Experiment Videos

Herpes simplex virus encephalitis simulating a frontoparietal convexity neoplasm.

R A Feldman, M C Shende

    Surgical Neurology
    |June 1, 1975
    PubMed
    Summary

    Herpes simplex virus can cause rare, localized encephalitis, mimicking rapidly expanding brain lesions. Definitive diagnosis requires neurosurgical intervention and brain biopsy, not just imaging.

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    Area of Science:

    • Neurology
    • Virology
    • Pathology

    Background:

    • Herpes simplex virus (HSV) is a common cause of sporadic encephalitis.
    • Encephalitis typically presents as a diffuse brain inflammation.

    Observation:

    • This case details an unusual, focal encephalitis caused by HSV.
    • The lesion was confined to the frontoparietal convexity, resembling a rapidly expanding mass.

    Findings:

    • Brain scanning and cerebral angiography showed limited diagnostic utility for this focal encephalitis.
    • Neurosurgical intervention and brain biopsy were essential for definitive diagnosis.

    Implications:

    • Clinicians should consider HSV encephalitis in the differential diagnosis of rapidly expanding brain lesions.
    • Early consideration of this rare presentation can guide diagnostic and treatment strategies.

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