Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Necrotizing enterocolitis in the newborn: operative indications.

J A O'Neill, M T Stahlman, H C Meng

    Annals of Surgery
    |September 11, 1975
    PubMed
    Summary

    Necrotizing enterocolitis (NEC) in premature infants often requires surgery. A significant drop in platelet count reliably indicates gangrenous bowel, necessitating prompt surgical intervention for improved survival rates.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evaluating team-based inter-professional advanced life support training in intensive care-a prospective observational study.

    Anaesthesia and intensive care·2017
    Same author

    ASSESSMENT AND CARE OF NEWBORN PROBLEMS.

    A listing of research in the cardiovascular field·2014
    Same author

    Interpleural analgesia following hepatic resection.

    Anaesthesia·2011
    Same author

    Pulsed white light dye laser system: a theoretical study.

    Applied optics·2010
    Same author

    Relationship between dobutamine echocardiography and the elevation of cardiac troponin I in patients with acute coronary syndromes.

    Echocardiography (Mount Kisco, N.Y.)·2001
    Same author

    Laparoscopic versus open splenectomy in the pediatric population: a contemporary single-center experience.

    The American surgeon·2001

    Area of Science:

    • Neonatal surgery
    • Pediatric gastroenterology
    • Critical care medicine

    Background:

    • Necrotizing enterocolitis (NEC) is a serious condition in premature, low birth weight infants.
    • Pneumatosis intestinalis is a common radiographic finding in NEC.

    Purpose of the Study:

    • To evaluate the effectiveness of medical and surgical management for NEC.
    • To identify reliable indicators for surgical intervention in NEC.

    Main Methods:

    • Retrospective review of 52 premature infants with NEC.
    • Analysis of treatment outcomes for medically and surgically managed patients.
    • Correlation of clinical, radiographic, and laboratory findings with disease progression and outcomes.

    Main Results:

    Related Experiment Videos

    • Overall survival was 66%.
    • Medical management (gastric decompression, antibiotics, supportive care, hyperalimentation) resulted in a 69% survival rate for 32 patients.
    • 20 patients required surgery, with 12 surviving (60% survival).
    • A sudden drop in platelet count below 100,000 reliably predicted gangrenous bowel and the need for operation.
    • Disseminated intravascular coagulation was associated with bowel gangrene.

    Conclusions:

    • Early surgical intervention is crucial for NEC patients with signs of deterioration or perforation.
    • Platelet count drop is a highly sensitive predictor of NEC progression requiring surgery.
    • Gastrostomy, bowel resection, and staged anastomosis offer the best surgical outcomes.