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Can the increase in body mass index explain the rising trend in asthma in children?
1Department of Public Health Sciences, King's College London, London SE1 3QD, UK. sue.chinn@kcl.ac.uk
Insights
Rising childhood obesity does not explain the increasing prevalence of asthma. The link between asthma and obesity appears recent, possibly due to lifestyle changes affecting both conditions.
Area of Science:
- Pediatric Health
- Epidemiology
- Respiratory Medicine
Background:
- The rising prevalence of childhood asthma and obesity has led to hypotheses linking the two conditions.
- Trends in asthma and obesity were examined in British children from 1982 to 1994.
Purpose of the Study:
- To investigate whether increasing obesity rates explain the rise in childhood asthma prevalence.
- To analyze the association between body mass index (BMI) and asthma symptoms over time.
Main Methods:
- Calculated odds ratios for asthma trends in 8- and 9-year-old children.
- Adjusted for body mass index (BMI) to assess its impact on asthma prevalence.
- Analyzed trends in wheeze and "asthma or bronchitis" as related outcomes.
Main Results:
- Odds ratios for asthma per year remained consistent before and after BMI adjustment in both boys and girls.
- Adjusted and unadjusted odds ratios for wheeze and "asthma or bronchitis" were nearly identical.
- The lack of adjustment effect was attributed to temporal changes in the BMI-symptom association.
Conclusions:
- Trends in overweight and obesity do not account for the increasing prevalence of asthma.
- The association between asthma and obesity appears to be a recent phenomenon.
- Obesity may serve as a marker for recent lifestyle shifts linked to both asthma and overweight conditions.
Background:
The reported association between asthma and obesity and the documented rise in each over time have led to suggestions that rising obesity might explain the increase in the prevalence of asthma. Trends in both in British children participating in the National Study of Health and Growth were marked from 1982 to 1994.
Methods:
Odd ratios for trends in asthma and symptoms in 8 and 9 year old children were calculated with and without adjustment for body mass index (BMI).
Results:
In a representative sample of white children the odds ratio per year for asthma was 1.09 (95% CI 1.07 to 1.11) before and after adjustment for BMI for boys and 1.09 (95% CI 1.07 to 1.12) and 1.09 (95% CI 1.05 to 1.12), respectively, for girls. Unadjusted and adjusted odds ratios were also virtually identical for wheeze and "asthma or bronchitis". The lack of effect of adjustment was due to a change in the association between BMI and symptoms with time.
Conclusions:
Trends in overweight and obesity do not explain the increase in asthma. The evidence points towards the association between asthma and obesity being of recent origin. This may be explained by obesity being a marker of recent lifestyle differences now associated with both asthma and overweight.
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