Related Experiment Video
Updated: Oct 4, 2026

Freezing Injury in Mouse Masseter Muscle to Establish an Orofacial Muscle Fibrosis Model
Published on: December 29, 2023
Unilateral fibroadipose degeneration of the masticatory muscles
E Pomatto1, S Castellano, S D Bianchi
1Department of Clinical Physiopathology, University of Turin, Turin, Italy.
Abstract:
A unique case of fatty replacement of the masticatory muscles, causing progressive limitation of mouth opening, is presented. Both CT and MRI revealed an almost total substitution of the masticatory muscles with fatty tissue, confirmed by the histopathology at surgery. Myotomy of masseter and internal pterygoid muscles and coronoidotomy improved his symptoms. There is no known cause of fibroadipose replacement of muscle fibres.
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