Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Focal eosinophilic myositis.

Y Kobayashi¹, T Fujimoto, H Shiiki

¹First Department of Internal Medicine, Nara Medical University, Japan.

Clinical Rheumatology

|October 20, 2001

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Renal arteriolar hyalinosis, not intimal thickening in large arteries, is associated with cardiovascular events in people with biopsy-proven diabetic nephropathy.

Diabetic medicine : a journal of the British Diabetic Association·2020

Same author

Tubulointerstitial macrophage infiltration in a patient with hypokalemic nephropathy and primary Sjögren's syndrome.

Clinical nephrology·2005

Same author

Expression of Bcl-2 and Bax in hypokalemic nephropathy in rats.

Pathobiology : journal of immunopathology, molecular and cellular biology·2002

Same author

Primary Sjögren's syndrome presenting as hypokalaemic periodic paralysis and respiratory arrest.

Clinical rheumatology·2001

Same author

[CHF arising after low dose THP-COP chemotherapy in an elderly patient with malignant lymphoma].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·2001

Same author

[Two cases of exercise-induced acute renal failure with idiopathic renal hypouricemia].

Nihon Jinzo Gakkai shi·2001

Idiopathic hypereosinophilic syndrome (HES) can manifest as focal eosinophilic myositis, causing muscle swelling and weakness. Corticosteroids effectively treated this uncommon HES complication in a reported case.

Area of Science:

Rheumatology
Neurology
Hematology

Background:

Idiopathic hypereosinophilic syndrome (HES) is a rare disorder characterized by persistent eosinophilia and organ damage.
Focal eosinophilic myositis is an infrequent but significant manifestation of HES.

Observation:

A patient presented with tender muscle swelling and proximal weakness in the lower limbs.
Clinical presentation lacked systemic symptoms and muscle atrophy.
Muscle biopsy revealed acute myositis with significant eosinophil infiltration.

Findings:

Electromyography confirmed myositis.
The patient showed an excellent clinical and biochemical response to corticosteroid therapy.
A relapse occurred due to insufficient steroid dose reduction but responded well to treatment.

Related Experiment Videos

Implications:

This case highlights focal eosinophilic myositis as a treatable HES manifestation.
Early diagnosis and appropriate corticosteroid management are crucial for HES-related myositis.
Further research into HES subtypes and targeted therapies is warranted.