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Evaluation of Mammary Gland Development and Function in Mouse Models
Published on: July 21, 2011
The failure of prolactin to initiate lactogenesis in the ewe
Australian Journal of Biological Sciences
|June 1, 1979
Abstract:
Infusion of exogenous prolactin (NIH-P-S11) at 1 mg/h for 10 h into ewes pretreated for 30 days with oestradiol benzoate and progesterone was unable to initiate milk secretion. Similarly primed ewes injected with 10 microgram thyrotrophin releasing hormone also failed to lactate but all ewes injected with dexamethasone (10 mg daily for 5 days) after oestrogen plus progesterone treatment secreted copious quantities of milk. The results suggest that prolactin, itself, is not capable of initiating lactogenesis in the ewe.
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