Related Experiment Video

Updated: Oct 3, 2026

Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface
10:38

Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface

Published on: October 8, 2013

[Connection between changes in the nasal and mouth mucosa with immune status under the effect of environmental

N N Beliaeva, A A Shamarin, I V Petrova

    Gigiena I Sanitariia
    |October 23, 2001
    PubMed

    Insights

    This study examined the cytological status of nasal and oral mucosa in Russian children. Environmental pollution in Klimovsk correlated with changes in mucosa, immunity, and illness rates.

    Area of Science:

    • Environmental Science
    • Cytology
    • Public Health

    Context:

    • Assesses the health of preschool and school children across various Russian Federation locations.
    • Investigates the cytological status of nasal and oral mucosae.
    • Includes data from Moscow, Klimovsk, and Yaroslavl.

    Purpose:

    • To determine the cytological status of nasal and oral mucosae in children.
    • To explore the relationship between mucosal status, immunity, and morbidity.
    • To examine the influence of environmental pollution on these factors.

    Summary:

    • Cytological analysis of nasal and oral mucosa was performed on 789 children.
    • A correlation was observed between mucosal status, immune response, and illness.
    • The town of Klimovsk served as a case study, linking environmental pollution to observed health indicators.

    Impact:

    • Highlights the impact of environmental factors on children's mucosal health and immunity.
    • Provides data for public health initiatives in polluted areas.
    • Establishes a link between environmental quality and pediatric health outcomes.

    More Related Videos

    Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels05:31

    Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

    Published on: August 7, 2017

    Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay06:08

    Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

    Published on: September 22, 2023

    Related Concept Videos

    The Oral Microbiota01:27

    The Oral Microbiota

    The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
    Microbiota of the Respiratory Tract01:29

    Microbiota of the Respiratory Tract

    The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
    Factors Affecting the Risk of Infection01:26

    Factors Affecting the Risk of Infection

    The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
    The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
    Development of the Oral Microbiota01:28

    Development of the Oral Microbiota

    The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
    Nose and Nasal Cavity01:24

    Nose and Nasal Cavity

    The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...