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Serum TNF-alpha level in the neoplasm patients qualified for surgical treatment
H Gendek-Kubiak1, J Grzegorczyk, E G Gendek
1Department of Histology and Embryology, Medical University of Lódź, Poland. gawot@bg.am.lodz.pl
Abstract:
The aim of the study was to analyze serum tumor necrosis factor alpha (TNF-alpha) levels in patients with different neoplasm types qualified for surgical treatment and to evaluate their possible correlations with circulating immune complexes (CIC), IgG, IgM, and the complement (C) compounds: C1 inhibitor (C1i), C3c and C4 levels. Studies were performed in sera from 30 neoplasm patients before surgical treatment and in 10 persons from a control group (CG) with no malignancy. Serum TNF-alpha levels were measured with the Cytogen ELISA kit. Average TNF-alpha levels measured in neoplastic patient groups qualified for surgical treatment were not significantly different from the average TNF-alpha level in the CG group.