Related Experiment Video
Updated: Sep 30, 2026

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
Published on: April 4, 2014
Acylation of Alcohols and Amines with Vinyl Acetates Catalyzed by Cp(2)Sm(thf)(2)
Yasutaka Ishii1, Mitsuhiro Takeno, Yumi Kawasaki
1Department of Applied Chemistry, Faculty of Engineering, Kansai University, Suita, Osaka 564, Japan.
Abstract:
Cp(2)Sm(thf)(2) was found to be an efficient catalyst for the acylation of alcohols and amines with esters under mild conditions. In the present acylation, vinyl and isopropenyl acetates served as good acylating agents. Thus, a variety of alcohols and amines underwent acylation with vinyl and isopropenyl acetates in the presence of Cp(2)Sm(thf)(2) to give the corresponding esters and amides in good to excellent yields. This catalytic acylation of alcohols and amines offers an additional useful method by the use of various esters, instead of acid anhydrides and acid chlorides, as acylating agents under very mild conditions.
More Related Videos
Related Concept Videos
Acid-Catalyzed Dehydration of Alcohols to Alkenes
Aldehydes and Ketones with Alcohols: Hemiacetal Formation
Acetals and Thioacetals as Protecting Groups for Aldehydes and Ketones
In the presence of multiple functional groups, when selective reduction of one group over the other is desired, groups like aldehydes and ketones that form acetals...
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
Carboxylic Acids to Primary Alcohols: Hydride Reduction
Acid Halides to Esters: Alcoholysis

