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Updated: Aug 2, 2026
Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
Response of metastatic epidermoid anal cancer to single agent irinotecan: a case report
F Grifaichi1, A Padovani, F Romeo
1Department of Experimental Medicine, University La Sapienza, Policlinico Umberto I, Rome, Italy.
Abstract:
We report a case of a patient affected by epidermoid anal cancer who had hepatic progression after standard therapy with the Nigro regimen (fluorouracil and mitomycin C plus radiotherapy). This is an uncommon neoplasm against which only few chemotherapeutic agents have been tested. In our patient salvage treatment with low dose irinotecan resulted in a partial response.
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