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Updated: Oct 3, 2026
Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
Validation of a modified GTNM classification in peri-junctional oesophago-gastric carcinoma and its use as a
G H Dickson1, K K Singh, X Escofet
1Department of Gastroenterology, Worthing Hospital, West Sussex, BN11 2DH, UK. geo.m@talk21.com
Aim:
A modified GTNM classification (with additional T and N subdivisions) has been used for many years. The aim of this paper was to validate this classification in a group of patients with oesophago-gastric carcinoma and to see if the more detailed information may be useful.
Method:
The 3-year survival of 139 consecutive patients who survived resection has been related to the individual values of the modified and international classifications.
Results:
A step-wise reduction in the survival was found with increasing values of G, T, N and M. The international T3 value yielded a 17.7% survival rate, when subdivided, rates of 37.5%, 17.3% and 3.2% were found. The international N1 value yielded a rate of 12.9% which subdivided into rates of 25.0%, 18.7% and 7.5%.
Conclusion:
If these results are repeated in a larger and more detailed study, this modified classification may provide added information when discussing prognosis and management.