Kinesin, dynein and neurofilament transport
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Updated: Oct 3, 2026

Identification of Kinesin-1 Cargos Using Fluorescence Microscopy
Published on: February 14, 2016
1Center for Cellular Neurobiology and Neurodegeneration Research, Dept of Biological Sciences, University of Massachusetts Lowell, 01854, USA.Thomas_Shea@uml.edu
Abstract:
The recent demonstration that the fast axonal transport motors kinesin and dynein participate in axonal transport of neurofilaments--known to undergo slow transport--supports and extends recent studies indicating that some neurofilaments exhibit alternating bursts of fast axonal transport interspersed with periods of non-motility. In addition, these findings unify both certain aspects of axonal transport and neurofilament biology. We discuss these data herein in the context of both older and more recent studies of neurofilament dynamics.
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