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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
Published on: December 3, 2020
Drug and chemical blood-level data 2001
C L Winek1, W W Wahba, C L Winek
1Pittsburgh Criminalistics Laboratory, 1320 Fifth Avenue, Pittsburgh, PA 15219, USA. drwinek@aol.com
Forensic Science International
|October 24, 2001
Summary
This study updates blood-level data for toxicologically relevant drugs and chemicals. It provides current therapeutic, toxic, and lethal concentration ranges for accurate assessment.
Area of Science:
- Toxicology
- Pharmacology
- Clinical Chemistry
Background:
- Accurate blood-level data are crucial for diagnosing and managing drug toxicity.
- Previous compilations require regular updates due to new substances and evolving clinical data.
Purpose of the Study:
- To present current blood-level data for drugs and chemicals of toxicologic interest.
- To update previously published compilations of therapeutic, toxic, and lethal blood-levels.
Main Methods:
- Compilation and synthesis of existing literature.
- Data extraction and organization of blood concentration ranges.
Main Results:
- Provides an updated reference for therapeutic, toxic, and lethal blood concentrations.
- Includes a range of commonly encountered drugs and chemicals.
Conclusions:
- This updated data serves as a vital resource for toxicologists and clinicians.
- Facilitates informed decision-making in cases of drug overdose or poisoning.
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