A rare cause of intracranial hemorrhage: factor X deficiency

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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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A Citak1, R Uçsel, M Karaböcüoglu

  • 1Department of Pediatric Emergency Istanbul University Institute of Child Health, Istanbul, Turkey.

Pediatric Emergency Care
|October 24, 2001
PubMed

Congenital factor X deficiency is a rare inherited coagulation disorder, characterized by prolonged prothrombin time and partial thromboplastin time. For the definite diagnosis, specific factor X level should be investigated. We describe a patient with factor X deficiency who had intracranial hemorrhage. Hematologic tests showed prolonged prothrombin time, partial thromboplastin time, and a factor X level of 5%. The patient's hemorrhage resolved with fresh frozen plasma replacement. In this article, we discuss the clinical features and management of factor X deficiency.

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