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Calcification in invasive tracheal aspergillosis demonstrated on ultrasound: a new finding
A E Drury1, R A Allan, H Underhill
1Department of Radiology, St George's Hospital NHS Trust, Blackshaw Road, London SW17 0QT, UK.
The British Journal of Radiology
|October 25, 2001
Abstract:
Invasion of the major airways is a rare manifestation of respiratory tract involvement by Aspergillus sp. and is seen almost exclusively in immunocompromised patients. We present calcification as a new feature of this condition and its demonstration by ultrasound in a 15-year-old boy with severe neutropenia secondary to aplastic anaemia.
Insights
Invasive Aspergillus airway disease is rare in immunocompromised patients. This study highlights calcification as a new imaging feature, visualized by ultrasound in a neutropenic adolescent.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Invasive Aspergillus species infections of the major airways are uncommon, primarily affecting immunocompromised individuals.
- Respiratory tract involvement by Aspergillus is a serious condition requiring accurate diagnosis.
Observation:
- A 15-year-old boy with severe neutropenia due to aplastic anemia presented with respiratory symptoms.
- Initial imaging may not reveal all features of invasive airway disease.
Findings:
- Calcification within the affected airways was observed as a novel finding.
- Ultrasound successfully demonstrated this airway calcification, aiding in diagnosis.
Implications:
- Calcification represents a new imaging characteristic of invasive Aspergillus airway disease.
- Ultrasound may be a valuable tool for detecting airway calcification in at-risk patients.
- Early identification of such features can improve management strategies for invasive fungal infections.