Related Experiment Videos
Simple synthesis of climacostol, a defensive secretion by the ciliate Climacostomum virens
1Department of Mathematics and Science Education, Graduate School of Science, Science University of Tokyo, Japan.
Bioscience, Biotechnology, and Biochemistry
|October 26, 2001
Abstract:
Climacostol [1,3-dihydroxy-5-[(Z)-2'-nonenyl]benzene, 1], a defensive secretion by the protozoan ciliate Climacostomum virens against predators, was synthesized in a 43% overall yield in three steps by starting from methyl 1,3-bis(tert-butyldimethylsilyloxy) phenylacetate (3).