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[IgE antibody determination].

T Nakagawa1

  • 1Department of Internal Medicine, St. Marianna University School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 26, 2001
PubMed
Summary

Identifying and removing causative allergens is crucial for managing allergic asthma. This review covers recent advancements in diagnostic methods like skin tests and in vitro IgE antibody measurements used in Japan.

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Area of Science:

  • Allergy and Immunology
  • Respiratory Medicine

Context:

  • Bronchial asthma is a common allergic disorder, with allergic reactions implicated in approximately 70% of cases.
  • Effective management necessitates identifying and eliminating causative allergens to alleviate symptoms and enhance patient quality of life.

Purpose:

  • To review recent advancements in diagnostic techniques for identifying allergens in patients with bronchial asthma.
  • To provide an overview of currently employed methods in Japan for allergy diagnosis.

Summary:

  • The review discusses various diagnostic approaches, including skin tests and in vitro immunoglobulin E (IgE) antibody measurements.
  • Specific in vitro methods covered are CAP RAST, Multiple Antigen Simultaneous Test (MAST), AlaSTAT, LUMIWARD, and Quidel Allergy Screen (QAS).
  • The Histamine Release Test (HRT) is also included as a diagnostic tool.

Impact:

  • Highlights the importance of accurate allergen identification for targeted asthma therapy.
  • Informs clinicians about the latest developments in allergy diagnostics for improved patient outcomes.
  • Facilitates better understanding and application of diverse allergy testing methods in clinical practice.

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