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Updated: Oct 3, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
[Surgical treatment of gastroesophageal reflux disease in adults]
M Huguier1, A Barrier, S Houry
1Service de chirurgie générale et digestive, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France. michel.huguier@tnn.ap-hop-paris.fr
Abstract:
Pathological gastroesophageal reflux is common. The aim of this review was to compare the results of different surgical techniques. Papers were selected on Medline from 1990 to April 2001. A critical analysis was performed, concerning definitions of included patients, surgical techniques, and criteria of evaluation. For comparison, the results of 23 randomized studies were mainly selected. Their heterogeneity has not allowed a meta-analysis. A few techniques had poorer results than others: simple closure of His angle, Hill operation, Belsey Mark IV technique, and Angelchik prosthesis. In most studies, results of partial fundoplication on reflux were as good as those of total Nissen fundoplication and fewer patients had postoperative dysphagia. In a double blind trial, immediate advantages of laparoscopic approach were less important than those observed in non comparative studies. Another trial was interrupted after inclusion of 103 patients because of the higher rate of side-effects in the laparoscopic group. These results may help the surgeon in the choice of a technique. Patients have to be informed of potential adverse effects of the different techniques chosen by their surgeon.
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